Compound Q&A
How is 5-Methoxy-2-{(S)-[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulfinyl}-1H-benzimidazole (CAS: 119141-88-7) typically synthesized?
Answer
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5-Methoxy-2-{(S)-[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulfinyl}-1H-benzimidazole is synthesized via a multi-step process involving the formation of the 4-methoxy-3,5-dimethyl-2-pyridine methyl sulfinyl group and subsequent coupling with 5-methoxy-1H-benzimidazole. Commonly, this synthesis involves the use of tert-butyl chloroformate as a coupling agent and triethylamine as a base. The overall yield is typically around 70-80%, with good selectivity for the desired product.
About
CAS No
119141-88-7
English Name
5-Methoxy-2-{(S)-[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulfinyl}-1H-benzimidazole
Molecular Formula
C17H19N3O3S
Molecular Weight
345.42 g/mol
SMILES
CC1=CN=C(C(=C1OC)C)CS(=O)C2=NC3=C(N2)C=C(C=C3)OC
InChIKey
SUBDBMMJDZJVOS-DEOSSOPVSA-N
Last Updated: 2025-09-08 00:42
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