How is 4-Nitrobenzyl (2S,4S)-4-(acetylsulfanyl)-2-{[{[(2-methyl-2-propanyl)oxy]carbonyl}(sulfamoyl)amino]methyl}-1-pyrrolidinecarboxylate (CAS: 491878-06-9) typically synthesized?

This compound is typically synthesized via a multi-step process involving acylation, sulfenylation, and amidation reactions. Key steps include the protection of the pyrrolidine hydroxyl group, followed by the introduction of the acetyl group and sulfanyl group, and finally the addition of the amidine moiety. This synthesis requires careful control of reaction conditions and the use of appropriate protecting groups.