Compound Q&A

How is 3-(4-Isopropylphenyl)-1,1-dimethylurea (CAS: 34123-59-6) typically synthesized?

Answer

3-(4-Isopropylphenyl)-1,1-dimethylurea
3-(4-Isopropylphenyl)-1,1-dimethylurea is typically synthesized by reacting 4-isopropylaniline with dimethylcarbonate in the presence of a base such as potassium carbonate. The reaction is conducted in a solvent like N,N-dimethylformamide (DMF) at elevated temperature (typically around 100°C). The yield is generally high, and the product is isolated by filtration and recrystallization.

About

CAS No 34123-59-6
English Name 3-(4-Isopropylphenyl)-1,1-dimethylurea
Molecular Formula C12H18N2O
Molecular Weight 206.29 g/mol
SMILES CC(C)C1=CC=C(C=C1)NC(=O)N(C)C
InChIKey PUIYMUZLKQOUOZ-UHFFFAOYSA-N
Last Updated: 2025-09-08 00:42

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