Compound Q&A

How is (2R,3S)-2-{[(2R)-2-Acetamido-3-(3-fluorophenyl)propanoyl]amino}-5-methoxy-4-(methoxycarbonyl)-3-methyl-5-oxopentanoic acid (CAS: 70955-01-0) typically synthesized?

Answer

(2R,3S)-2-{[(2R)-2-Acetamido-3-(3-fluorophenyl)propanoyl]amino}-5-methoxy-4-(methoxycarbonyl)-3-methyl-5-oxopentanoic acid
(2R,3S)-2-{[(2R)-2-Acetamido-3-(3-fluorophenyl)propanoyl]amino}-5-methoxy-4-(methoxycarbonyl)-3-methyl-5-oxopentanoic acid is synthesized via a multi-step process involving acylation, amidation, and esterification reactions. Commonly, this compound is prepared using reagents such as 3-(3-fluorophenyl)-2-aminopropanoic acid, acetic anhydride, and methanol under controlled conditions. The process yields a product with high purity and selectivity, making it suitable for various applications in fine chemistry.

About

CAS No 70955-01-0
English Name (2R,3S)-2-{[(2R)-2-Acetamido-3-(3-fluorophenyl)propanoyl]amino}-5-methoxy-4-(methoxycarbonyl)-3-methyl-5-oxopentanoic acid
Molecular Formula C20H25FN2O8
Molecular Weight 440.42 g/mol
SMILES C[C@H]([C@H](C(=O)O)NC(=O)[C@@H](Cc1cccc(c1)F)NC(=O)C)C(C(=O)OC)C(=O)OC
InChIKey FJUZEZRZKVMAMD-DRZCJDIDSA-N
Last Updated: 2025-09-08 00:42

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