Compound Q&A

How is 2-Isopropylidenehydrazinecarbothioamide (CAS: 1752-30-3) typically synthesized?

Answer

2-Isopropylidenehydrazinecarbothioamide
2-Isopropylidenehydrazinecarbothioamide is synthesized by the reaction of isopyrazolidone with hydrazine sulfate in the presence of a catalyst such as sulfuric acid. The reaction is carried out in water at elevated temperatures, followed by extraction with an organic solvent. The yield is typically around 70-80%, with good selectivity for the target product. The reaction is exothermic, and proper heat management is necessary to avoid decomposition.

About

CAS No 1752-30-3
English Name 2-Isopropylidenehydrazinecarbothioamide
Molecular Formula C4H9N3S
Molecular Weight 131.2 g/mol
SMILES CC(=NNC(=S)N)C
InChIKey FQUDPIIGGVBZEQ-UHFFFAOYSA-N
Last Updated: 2025-09-08 00:42

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