Compound Q&A
How is Ethyl amino(thioxo)acetate (CAS: 16982-21-1) typically synthesized?
Answer
Ethyl amino(thioxo)acetate can be synthesized via a multistep process involving the reaction of ethyl acetoacetate with thiourea in the presence of a base such as sodium hydroxide. The key steps include the formation of an intermediate thioacetal followed by nucleophilic substitution reactions. The overall yield is typically around 70-80%, with high selectivity towards the desired product.
About
CAS No
16982-21-1
English Name
Ethyl amino(thioxo)acetate
Molecular Formula
C4H7NO2S
Molecular Weight
133.17 g/mol
SMILES
CCOC(=O)C(=S)N
InChIKey
YMBMCMOZIGSBOA-UHFFFAOYSA-N
Last Updated: 2025-09-07 10:19
