Compound Q&A
How is N-(2-Chloro-6-fluorobenzyl)-N-ethyl-2,6-dinitro-4-(trifluoromethyl)aniline (CAS: 62924-70-3) typically synthesized?
Answer
N-(2-Chloro-6-fluorobenzyl)-N-ethyl-2,6-dinitro-4-(trifluoromethyl)aniline (CAS: 62924-70-3) is synthesized through a multi-step process involving the aromatic substitution of chlorobenzene with 2-fluorobenzyl chloride, followed by nitration and trifluoromethylation. Commonly, this process uses concentrated sulfuric acid for nitration and potassium trifluoromethanesulfonate for trifluoromethylation. The yield and selectivity are influenced by reaction conditions and the choice of catalysts.
About
CAS No
62924-70-3
English Name
N-(2-Chloro-6-fluorobenzyl)-N-ethyl-2,6-dinitro-4-(trifluoromethyl)aniline
Molecular Formula
C16H12ClF4N3O4
Molecular Weight
421.7308 g/mol
SMILES
CCN(CC1=C(F)C=CC=C1Cl)C1=C(C=C(C=C1[N+]([O-])=O)C(F)(F)F)[N+]([O-])=O
InChIKey
PWNAWOCHVWERAR-UHFFFAOYSA-N
Last Updated: 2025-09-07 10:19