Compound Q&A
How is Vonoprazan (CAS: 881681-00-1) typically synthesized?
Answer
Vonoprazan is synthesized via a multi-step process that involves acylation, alkylation, and condensation reactions. Key steps include the introduction of a trifluoromethyl group and an imidazole ring. The synthesis typically uses catalysts like sulfuric acid and employs high selectivity and yield, with the final product purified by recrystallization and chromatography.
About
CAS No
881681-00-1
English Name
Vonoprazan
Molecular Formula
C17H16FN3O2S
Molecular Weight
345.39900000000006 g/mol
SMILES
CNCC1=CN(C(=C1)C2=CC=CC=C2F)S(=O)(=O)C3=CN=CC=C3
InChIKey
BFDBKMOZYNOTPK-UHFFFAOYSA-N
Last Updated: 2025-09-07 10:19
