Compound Q&A
How is Methyl 5-chloro-2-hydroxybenzoate (CAS: 4068-78-4) typically synthesized?
Answer
Methyl 5-chloro-2-hydroxybenzoate is commonly synthesized via the esterification of 5-chloro-2-hydroxybenzoic acid with methanol. The reaction is typically catalyzed by an acid like sulfuric acid and proceeds under mild conditions to give a high yield of around 90%. Selectivity and purity can be enhanced by employing appropriate purification techniques.
About
CAS No
4068-78-4
English Name
Methyl 5-chloro-2-hydroxybenzoate
Molecular Formula
C8H7ClO3
Molecular Weight
186.59 g/mol
SMILES
COC(=O)C1=C(C=CC(=C1)Cl)O
InChIKey
KJWHRMZKJXOWFC-UHFFFAOYSA-N
Last Updated: 2025-09-07 10:19
