Compound Q&A
How is 2-Chloro-5-(trifluoromethyl)pyrimidine (CAS: 69034-12-4) typically synthesized?
Answer
2-Chloro-5-(trifluoromethyl)pyrimidine is typically synthesized via the reaction of 5-chloropyrimidine with trifluoroacetyl chloride in the presence of a base, such as triethylamine. The reaction is known to be highly selective and provides good yield. Various catalysts can be used to improve the reaction rate and selectivity.
About
CAS No
69034-12-4
English Name
2-Chloro-5-(trifluoromethyl)pyrimidine
Molecular Formula
C5H2ClF3N2
Molecular Weight
182.53 g/mol
SMILES
C1=C(C=NC(=N1)Cl)C(F)(F)F
InChIKey
TYCYTQLXAIDJNF-UHFFFAOYSA-N
Last Updated: 2025-09-07 10:19
