Compound Q&A

How is 5-(Trifluoromethyl)-2,4(1H,3H)-pyrimidinedione (CAS: 54-20-6) typically synthesized?

Answer

5-(Trifluoromethyl)-2,4(1H,3H)-pyrimidinedione
5-(Trifluoromethyl)-2,4(1H,3H)-pyrimidinedione (CAS: 54-20-6) can be synthesized through a variety of methods. One common approach involves the reaction of 2,4-dichloropyrimidine with trifluoroacetic anhydride. This method provides good yield and selectivity, and the use of a Lewis acid as a catalyst can enhance the reaction efficiency.

About

CAS No 54-20-6
English Name 5-(Trifluoromethyl)-2,4(1H,3H)-pyrimidinedione
Molecular Formula C5H3F3N2O2
Molecular Weight 180.08 g/mol
SMILES C1=C(C(=O)NC(=O)N1)C(F)(F)F
InChIKey LMNPKIOZMGYQIU-UHFFFAOYSA-N
Last Updated: 2025-09-07 10:19

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