Compound Q&A

How is 4-Acetylbenzonitrile (CAS: 1443-80-7) typically synthesized?

Answer

4-Acetylbenzonitrile
4-Acetylbenzonitrile (CAS: 1443-80-7) is commonly synthesized by acetylation of benzonitrile under acidic conditions. The reaction usually involves benzonitrile, acetic anhydride, and concentrated sulfuric acid as a catalyst. The yield is typically around 70-75% with good selectivity towards the acetylation product.

About

CAS No 1443-80-7
English Name 4-Acetylbenzonitrile
Molecular Formula C9H7NO
Molecular Weight 145.16 g/mol
SMILES CC(=O)C1=CC=C(C=C1)C#N
InChIKey NLPHXWGWBKZSJC-UHFFFAOYSA-N
Last Updated: 2025-09-07 10:19

Related Q&A

Compound Q&A

What are the physical and chemical properties of 4-Acetylbenzonitrile (CAS: 1443-80-7)?

4-Acetylbenzonitrile (CAS: 1443-80-7) is a colorless to white crystalline solid with a molecular wei...

Compound Q&A

What industries use 4-Acetylbenzonitrile (CAS: 1443-80-7)?

4-Acetylbenzonitrile (CAS: 1443-80-7) is used in the pharmaceutical industry for the synthesis of ce...

Compound Q&A

What precautions should be taken when handling 4-Acetylbenzonitrile (CAS: 1443-80-7)?

When handling 4-Acetylbenzonitrile (CAS: 1443-80-7), it is essential to use proper personal protecti...

Compound Q&A

What is 6-Methyl-7-oxabicyclo[4.1.0]heptan-2-one (CAS: 21889-89-4)?

6-Methyl-7-oxabicyclo[4.1.0]heptan-2-one is a cyclic ketone with a molecular for...

21889-89-46-Methyl-7-oxabicycl...
Compound Q&A

What is 4-[(6-Methyl-2-pyrazinyl)oxy]benzoic acid (CAS: 906353-00-2)?

4-[(6-Methyl-2-pyrazinyl)oxy]benzoic acid is a chemical compound with the CAS nu...

906353-00-24-[(6-Methyl-2-pyraz...
Compound Q&A

What is 2-(2-Pyridinyl)-1,3-propanediol (CAS: 49745-42-8)?

2-(2-Pyridinyl)-1,3-propanediol (CAS: 49745-42-8) is a colorless to slightly yel...

49745-42-82-(2-Pyridinyl)-1,3-...
Compound Q&A

What is 2-(6-Chloro-2-pyridinyl)-2-phenylacetonitrile (CAS: 24783-42-4)?

2-(6-Chloro-2-pyridinyl)-2-phenylacetonitrile is an organic compound with the CA...

24783-42-42-(6-Chloro-2-pyridi...