Compound Q&A

How is Dihydrostreptomycin sulfate (CAS: 5490-27-7) typically synthesized?

Answer

Dihydrostreptomycin sulfate
Dihydrostreptomycin sulfate is synthesized through the modification of streptomycin. The process involves the reduction of streptomycin sulfate to dihydrostreptomycin sulfate using sodium borohydride as a catalyst. The reaction is highly selective and yields a high percentage of the desired product. The product is then converted to sulfate by reacting with sulfuric acid in the presence of a suitable solvent.

About

CAS No 5490-27-7
English Name Dihydrostreptomycin sulfate
Molecular Formula C42H88N14O36S3
Molecular Weight 583.6 g/mol
SMILES CC1C(C(C(O1)OC2C(C(C(C(C2O)O)N=C(N)N)O)N=C(N)N)OC3C(C(C(C(O3)CO)O)O)NC)(CO)O.CC1C(C(C(O1)OC2C(C(C(C(C2O)O)N=C(N)N)O)N=C(N)N)OC3C(C(C(C(O3)CO)O)O)NC)(CO)O.OS(=O)(=O)O.OS(=O)(=O)O.OS(=O)(=O)O
InChIKey ASXBYYWOLISCLQ-HZYVHMACSA-N
Last Updated: 2025-09-07 10:19

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