Compound Q&A
How is Temsirolimus (CAS: 162635-04-3) typically synthesized?
Answer
Temsirolimus (CAS: 162635-04-3) is synthesized through a complex multi-step process that includes acylation, cyclization, and amidation reactions. A key step involves the use of a chiral catalyst for enantioselective synthesis. The overall process yields up to 85% of the desired product, with the final product purified by chromatography and crystallization.
About
CAS No
162635-04-3
English Name
Temsirolimus
Molecular Formula
C56H87NO16
Molecular Weight
1030.3 g/mol
SMILES
CC1CCC2CC(C(=CC=CC=CC(CC(C(=O)C(C(C(=CC(C(=O)CC(OC(=O)C3CCCCN3C(=O)C(=O)C1(O2)O)C(C)CC4CCC(C(C4)OC)OC(=O)C(C)(CO)CO)C)C)O)OC)C)C)C)OC
InChIKey
CBPNZQVSJQDFBE-FUXHJELOSA-N
Last Updated: 2025-09-07 10:19
