Compound Q&A
How is Alpha-Estradiol (CAS: 57-91-0) typically synthesized?
Answer
Alpha-Estradiol (CAS: 57-91-0) is synthesized by various methods, including reduction of estrone, hydroxylation of estrone, or direct synthesis from benzaldehyde and acetic anhydride. Common catalysts include sodium borohydride or potassium hydroxide. The reaction is typically carried out in organic solvents with high yields and good selectivity.
About
CAS No
57-91-0
English Name
Alpha-Estradiol
Molecular Formula
C18H24O2
Molecular Weight
272.39 g/mol
SMILES
C[C@]12CC[C@H]3[C@@H](CCC4=C3C=CC(O)=C4)[C@@H]1CC[C@H]2O
InChIKey
VOXZDWNPVJITMN-SFFUCWETSA-N
Last Updated: 2025-09-07 10:18
