Compound Q&A
How is N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-D-tryptophan (CAS: 86123-11-7) typically synthesized?
Answer
![N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-D-tryptophan](https://static.chemtradehub.com/structs/861/86123-11-7-787a.webp "N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-D-tryptophan")
N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-D-tryptophan is typically synthesized through a multi-step process involving the protection of tryptophan with a fluorenylmethoxycarbonyl (Fmoc) group. This involves the coupling of Fmoc-protected tryptophan with fluorenylmethanol using a suitable coupling reagent, followed by deprotection to yield the desired product with high selectivity and yield.
About
CAS No
86123-11-7
English Name
N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-D-tryptophan
Molecular Formula
C26H22N2O4
Molecular Weight
426.47 g/mol
SMILES
OC(=O)[C@@H](Cc1c[nH]c2ccccc12)NC(=O)OCC3c4ccccc4-c5ccccc35
InChIKey
MGHMWKZOLAAOTD-XMMPIXPASA-N
Last Updated: 2025-09-07 10:18
![N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-D-tryptophan — Shanghai Yuyeh Biotechnology Co., Ltd.](https://static.chemtradehub.com/suppliers/67ce9f132b2de6e8e95a48fe/67ce9f132b2de6e8e95a48fe-logo.webp){kind=logo}
![N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-D-tryptophan — Shanghai Yinxin Laboratory Equipment Co., Ltd.](https://static.chemtradehub.com/suppliers/67cdd97a57537e5c8069adfb/67cdd97a57537e5c8069adfb-logo.webp){kind=logo}
![N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-D-tryptophan — ShangHaiMaiRuiErShengHua Technology Co Ltd](https://static.chemtradehub.com/suppliers/67ced3b52b2de6e8e95a6e52/67ced3b52b2de6e8e95a6e52-logo.webp){kind=logo}