Compound Q&A

How is 8-Chloro-5,6-dihydro-11H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-one (CAS: 31251-41-9) typically synthesized?

Answer

8-Chloro-5,6-dihydro-11H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-one
8-Chloro-5,6-dihydro-11H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-one can be synthesized through a multi-step process involving acylation, cyclization, and chlorination. Commonly, a pyridine derivative is first acylated, then cyclized to form the core structure, and finally chlorinated to introduce the chlorine substituent. The reaction conditions include the use of acylating agents like acid chlorides and bases such as sodium hydride.

About

CAS No 31251-41-9
English Name 8-Chloro-5,6-dihydro-11H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-one
Molecular Formula C14H10ClNO
Molecular Weight 243.69 g/mol
SMILES C1CC2=C(C=CC(=C2)Cl)C(=O)C3=C1C=CC=N3
InChIKey WMQNOYVVLMIZDV-UHFFFAOYSA-N
Last Updated: 2025-09-07 10:18

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