Compound Q&A
How is 2-Bromo-4-fluorobenzaldehyde (CAS: 59142-68-6) typically synthesized?
Answer
2-Bromo-4-fluorobenzaldehyde (CAS: 59142-68-6) is commonly synthesized via bromination of 4-fluorobenzaldehyde using N-bromosuccinimide (NBS) in the presence of a radical initiator like AIBN. The reaction involves electrophilic aromatic substitution, followed by reduction of the bromo group to form the aldehyde. The yield is around 70-80%, and the process is conducted under mild conditions to ensure high selectivity.
About
CAS No
59142-68-6
English Name
2-Bromo-4-fluorobenzaldehyde
Molecular Formula
C7H4BrFO
Molecular Weight
203.01 g/mol
SMILES
C1=CC(=C(C=C1F)Br)C=O
InChIKey
OPZDXMCOWFPQPE-UHFFFAOYSA-N
Last Updated: 2025-09-07 10:18
