Compound Q&A

How is Dimethyl 2,5-pyridinedicarboxylate (CAS: 881-86-7) typically synthesized?

Answer

Dimethyl 2,5-pyridinedicarboxylate
Dimethyl 2,5-pyridinedicarboxylate (CAS: 881-86-7) is typically synthesized via the esterification of 2,5-pyridinedicarboxylic acid with dimethyl carbonate. Commonly used catalysts include magnesium sulfate or aluminum chloride. The reaction is carried out under mild conditions, and the high selectivity and high yield make this method a standard in industrial synthesis.

About

CAS No 881-86-7
English Name Dimethyl 2,5-pyridinedicarboxylate
Molecular Formula C9H9NO4
Molecular Weight 195.17 g/mol
SMILES COC(=O)c1ccc(nc1)C(=O)OC
InChIKey TUGSJNQAIMFEDY-UHFFFAOYSA-N
Last Updated: 2025-09-07 10:18

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