Compound Q&A
How is 5'-Deoxy-5-fluorocytidine (CAS: 66335-38-4) typically synthesized?
Answer
5'-Deoxy-5-fluorocytidine is typically synthesized via a six-step process starting from cytosine. The key steps involve fluorination of cytosine to form 5-fluorocytosine, followed by coupling with 5'-deoxyribose. Commonly used catalysts include palladium(II) acetate for the coupling reaction, and the overall yield is around 70-80%.
About
CAS No
66335-38-4
English Name
5'-Deoxy-5-fluorocytidine
Molecular Formula
C9H12FN3O4
Molecular Weight
245.21 g/mol
SMILES
CC1C(C(C(O1)N2C=C(C(=NC2=O)N)F)O)O
InChIKey
YSNABXSEHNLERR-ZIYNGMLESA-N
Last Updated: 2025-09-07 10:18
