Compound Q&A

How is N-[(3alpha,5beta,7beta,8xi)-3,7-Dihydroxy-24-oxocholan-24-yl]glycine (CAS: 64480-66-6) typically synthesized?

Answer

N-[(3alpha,5beta,7beta,8xi)-3,7-Dihydroxy-24-oxocholan-24-yl]glycine
N-[(3alpha,5beta,7beta,8xi)-3,7-Dihydroxy-24-oxocholan-24-yl]glycine (CAS: 64480-66-6) is synthesized through a multi-step process involving the synthesis of the cholan-24-one ring, followed by hydroxylation, and finally the coupling with glycine. Common catalysts include metal complexes, and the yield is typically around 70-80%.

About

CAS No 64480-66-6
English Name N-[(3alpha,5beta,7beta,8xi)-3,7-Dihydroxy-24-oxocholan-24-yl]glycine
Molecular Formula C26H43NO5
Molecular Weight 449.63 g/mol
SMILES O=C(O)CNC(CC[C@@H](C)[C@H]1CC[C@@]2([H])[C@]3([H])[C@@H](O)C[C@]4([H])C[C@H](O)CC[C@]4(C)[C@@]3([H])CC[C@]12C)=O
InChIKey GHCZAUBVMUEKKP-XROMFQGDSA-N
Last Updated: 2025-09-07 10:18

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