Compound Q&A

How is 1,2-Dimethyl-1H-indole (CAS: 875-79-6) typically synthesized?

Answer

1,2-Dimethyl-1H-indole
1,2-Dimethyl-1H-indole (CAS: 875-79-6) is typically synthesized via the indole synthesis route, where an indole ring is formed from an aldehyde and a substituted aniline under basic conditions. The reaction involves the condensation of acetaldehyde and 2,3-dimethylaniline in the presence of a base such as sodium hydroxide. This method provides good yield and selectivity.

About

CAS No 875-79-6
English Name 1,2-Dimethyl-1H-indole
Molecular Formula C10H11N
Molecular Weight 145.2 g/mol
SMILES Cc1cc2ccccc2n1C
InChIKey BJMUOUXGBFNLSN-UHFFFAOYSA-N
Last Updated: 2025-09-07 10:18

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