Compound Q&A

How is N-{4-[(4S)-2,5-Dioxo-1,3-oxazolidin-4-yl]butyl}-2,2,2-trifluoroacetamide (CAS: 42267-27-6) typically synthesized?

Answer

N-{4-[(4S)-2,5-Dioxo-1,3-oxazolidin-4-yl]butyl}-2,2,2-trifluoroacetamide
N-{4-[(4S)-2,5-Dioxo-1,3-oxazolidin-4-yl]butyl}-2,2,2-trifluoroacetamide can be synthesized via a multistep process involving the condensation of 4-(2,5-dioxo-1,3-oxazolidin-4-yl)butanoic acid with 2,2,2-trifluoroacetyl chloride. The reaction typically requires a suitable base such as triethylamine and is performed in anhydrous conditions to avoid side reactions. The yield can be optimized by using appropriate solvents and maintaining temperature and pH within optimal ranges.

About

CAS No 42267-27-6
English Name N-{4-[(4S)-2,5-Dioxo-1,3-oxazolidin-4-yl]butyl}-2,2,2-trifluoroacetamide
Molecular Formula C9H11F3N2O4
Molecular Weight 268.191 g/mol
SMILES C(CCNC(=O)C(F)(F)F)CC1C(=O)OC(=O)N1
InChIKey KWNIHCJDDYRQFW-YFKPBYRVSA-N
Last Updated: 2025-09-07 00:47

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