Compound Q&A

Are there alternatives to 1-[4-(Trifluoromethyl)phenyl]ethanone (CAS: 709-63-7) in synthesis?

Answer

1-[4-(Trifluoromethyl)phenyl]ethanone
While 1-[4-(Trifluoromethyl)phenyl]ethanone (CAS: 709-63-7) is a key intermediate in synthesis, there are alternative reagents and compounds that can serve similar roles. For instance, trifluoromethylbenzaldehyde can be used as an equivalent in certain reactions. Other alternatives include trifluoromethylbenzylamine, which can be converted to the desired ketone through oxidation. These alternatives are often chosen based on availability, cost, and the specific requirements of the synthetic pathway.

About

CAS No 709-63-7
English Name 1-[4-(Trifluoromethyl)phenyl]ethanone
Molecular Formula C9H7F3O
Molecular Weight 188.14799999999994 g/mol
SMILES CC(=O)C1=CC=C(C=C1)C(F)(F)F
InChIKey HHAISVSEJFEWBZ-UHFFFAOYSA-N
Last Updated: 2025-09-06 09:47

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