Compound Q&A

How is 2-Bromo-6-fluoroaniline (CAS: 65896-11-9) typically synthesized?

Answer

2-Bromo-6-fluoroaniline
2-Bromo-6-fluoroaniline (CAS: 65896-11-9) is typically synthesized through a coupling reaction of 6-fluoroaniline with bromine in the presence of a phase transfer catalyst, such as tetrabutylammonium bromide. The reaction proceeds under alkaline conditions to favor the formation of the brominated product. The yield is generally high, and the method provides good selectivity for the desired product.

About

CAS No 65896-11-9
English Name 2-Bromo-6-fluoroaniline
Molecular Formula C6H5BrFN
Molecular Weight 190.02 g/mol
SMILES C1=CC(=C(C(=C1)Br)N)F
InChIKey ALZFPYUPNVLVQM-UHFFFAOYSA-N
Last Updated: 2025-09-05 20:45

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