Compound Q&A

How is N,N-Dimethyl-N-[3-(trimethoxysilyl)propyl]-1-octadecanaminium chloride (CAS: 27668-52-6) typically synthesized?

Answer

N,N-Dimethyl-N-[3-(trimethoxysilyl)propyl]-1-octadecanaminium chloride
N,N-Dimethyl-N-[3-(trimethoxysilyl)propyl]-1-octadecanaminium chloride is typically synthesized through an amination reaction involving 1-octadecanamine, trimethoxysilylpropyl chloride, and dimethylamine. The reaction is catalyzed by a Lewis acid such as titanium(IV) chloride, leading to a high yield of the product with good selectivity. The reaction is usually carried out in a solvent like dichloromethane under anhydrous conditions.

About

CAS No 27668-52-6
English Name N,N-Dimethyl-N-[3-(trimethoxysilyl)propyl]-1-octadecanaminium chloride
Molecular Formula C26H58ClNO3Si
Molecular Weight 496.3 g/mol
SMILES CCCCCCCCCCCCCCCCCC[N+](C)(C)CCC[Si](OC)(OC)OC.[Cl-]
InChIKey WSFMFXQNYPNYGG-UHFFFAOYSA-M
Last Updated: 2025-09-05 20:45

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