Compound Q&A

What are the main uses of Monomethyl auristatin E (CAS: 474645-27-7)?

Answer

Monomethyl auristatin E
MMAE is primarily used in oncology as part of antibody-drug conjugates (ADCs). It targets cancer cells by attaching to monoclonal antibodies, delivering cytotoxic effects to malignant cells while minimizing damage to healthy tissues.

About

English Name Monomethyl auristatin E
Molecular Formula C39H67N5O7
Molecular Weight 717.993 g/mol
SMILES CCC(C)C(C(CC(=O)N1CCCC1C(C(C)C(=O)NC(C)C(C2=CC=CC=C2)O)OC)OC)N(C)C(=O)C(C(C)C)NC(=O)C(C(C)C)NC
InChIKey DASWEROEPLKSEI-UIJRFTGLSA-N
Last Updated: 2025-09-03 20:19

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