Compound Q&A

What are the main uses of Neratinib (CAS: 698387-09-6)?

Answer

Neratinib
Neratinib is primarily used in the treatment of HER2-positive breast cancer, especially in patients who have previously been treated with trastuzumab and pertuzumab. It is also being studied for its potential applications in other cancer types, including non-small cell lung cancer and gastrointestinal cancers. As a pharmaceutical compound, Neratinib is valued for its role in targeted therapy and its ability to inhibit multiple kinases involved in cancer progression.

About

English Name Neratinib
Molecular Formula C30H29ClN6O3
Molecular Weight 557 g/mol
SMILES CCOC1=C(C=C2C(=C1)N=CC(=C2NC3=CC(=C(C=C3)OCC4=CC=CC=N4)Cl)C#N)NC(=O)C=CCN(C)C
InChIKey JWNPDZNEKVCWMY-VQHVLOKHSA-N
Last Updated: 2025-08-25 01:08

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