Is psi,psi-Carotene (CAS: 502-65-8) safe?

Psi,psi-Carotene (CAS: 502-65-8) is generally recognized as safe (GRAS) when consumed in normal dietary amounts. However, excessive intake may lead to toxicity, such as carotenosis, causing skin discoloration. Proper handling with gloves and ventilation is recommended to avoid skin or eye contact. It meets safety standards for food use, but caution is advised in industrial or research settings to ensure appropriate exposure limits.