(2-CHLORO-5-PYRIDYL)METHYLZINC CHLORIDE 0.5 M IN TETRAHYDROFURAN(CAS: 352530-36-0)

Chloro[(6-chloro-3-pyridinyl)methyl]zinc (CAS: 352530-36-0) is a crystalline compound with a molecular weight of approximately 283.26 g/mol. It has limited water solubility, with a low solubility of 0.01 g/L at 25°C. The compound is moderately reactive with strong nucleophiles and bases. It is typically stable under normal atmospheric conditions but should be stored in a cool, dry place away from direct sunlight.

Chloro[(6-chloro-3-pyridinyl)methyl]zinc (CAS: 352530-36-0) is synthesized by reacting 6-chloro-3-pyridinylmethyl bromide with zinc in the presence of a suitable base, such as potassium carbonate. The reaction is typically conducted in an inert solvent like dimethylformamide (DMF) and yields the zinc compound with good selectivity and moderate yield (around 70%).

Chloro[(6-chloro-3-pyridinyl)methyl]zinc (CAS: 352530-36-0) is used primarily in the pharmaceutical industry for the synthesis of certain organic compounds and functional materials. It also has applications in the polymer and semiconductor industries due to its reactivity and ability to form stable complexes.

When handling Chloro[(6-chloro-3-pyridinyl)methyl]zinc (CAS: 352530-36-0), it is essential to use proper personal protective equipment (PPE), including gloves, goggles, and a lab coat. The compound should be handled in a well-ventilated area or a fume hood to minimize exposure. Spills should be cleaned up using appropriate tools and materials, and the area should be well-ventilated. Always refer to the Safety Data Sheet (SDS) for detailed handling and disposal instructions.