(2,4-DIMETHYL-THIAZOL-5-YL)-ACETIC ACID(CAS: 92933-49-8)

3-Isobutyl-1H-pyrazole-5-carboxylic acid is a white to off-white crystalline solid with a molecular weight of approximately 180.25. It is moderately soluble in water and ethanol but poorly soluble in most organic solvents. Reactivity is moderate, with typical carboxylic acid properties such as weak acidity and ester formation. It is stable under normal conditions but should be stored in a dry, cool place away from strong acids and bases.

3-Isobutyl-1H-pyrazole-5-carboxylic acid is commonly synthesized via the reaction of 3-isobutyl-1H-pyrazole with a carboxylation agent like carbon dioxide or carbon monoxide in the presence of a catalyst. The reaction is highly selective and yields 90% to 95% of the product, with minimal by-products.

3-Isobutyl-1H-pyrazole-5-carboxylic acid is used in the pharmaceutical industry for the synthesis of certain drug candidates. It is also utilized in the polymer industry to improve the properties of polymers, and in the sensor and semiconductor industries for specific applications requiring organic compounds with unique functional groups.

When handling 3-Isobutyl-1H-pyrazole-5-carboxylic acid, it is important to use proper personal protective equipment (PPE) such as gloves, goggles, and lab coats. The compound should be stored in a fume hood and handled in a well-ventilated area. In case of a spill, it should be handled according to the safety data sheet (SDS) guidelines to avoid exposure and to prevent environmental contamination. Always refer to the latest SDS for detailed safety information.