DPPS, NA(CAS: 145849-32-7)

1,2-Dipalmitoyl-SN-glycero-3-phospho-L-serine (monosodium salt) is a white crystalline powder with a molecular weight of approximately 695.86 g/mol. It has a limited solubility in water and is relatively stable under normal conditions. However, it can undergo hydrolysis under acidic or basic conditions. This compound is not highly reactive, but it can be sensitive to strong oxidizing agents.

This compound can be synthesized through the condensation of palmitoyl-CoA with 1,2-diacyl-sn-glycerol and L-serine. The synthesis typically involves a nucleophilic substitution reaction followed by a condensation step. Commonly, palladium catalysts are used to improve the yield and selectivity of the reaction. The product is then converted to the monosodium salt form for better solubility and stability.

1,2-Dipalmitoyl-SN-glycero-3-phospho-L-serine (monosodium salt) is primarily used in the pharmaceutical industry for its potential as a biomarker and in the development of certain drugs. It is also utilized in the polymer industry as a phospholipid precursor. Additionally, it has applications in sensor technology and semiconductor manufacturing as a component in certain materials.

When handling 1,2-Dipalmitoyl-SN-glycero-3-phospho-L-serine (monosodium salt), it is advisable to wear appropriate personal protective equipment (PPE) such as gloves and safety goggles. Store the compound in a cool, dry place away from direct sunlight and heat sources. Use a fume hood during preparation and disposal to minimize inhalation risk. Always refer to the Safety Data Sheet (SDS) for detailed guidance on safe handling and disposal.