[3-(4-FLUOROPHENYL)-5-METHYLISOXAZOLE-4-YL]-METHANOL(CAS: 1018297-63-6)

[3-(4-Fluorophenyl)-5-methyl-1,2-oxazol-4-yl]methanol is a white crystalline solid with a molecular weight of approximately 241.22 g/mol. It has a moderate solubility in water (2.8 g/L at 25°C) and is sparingly soluble in organic solvents like ethanol and methanol. Chemically, it is stable under normal conditions but can react with strong bases. It is soluble in methanol, ethanol, and acetone, but insoluble in water.

[3-(4-Fluorophenyl)-5-methyl-1,2-oxazol-4-yl]methanol can be synthesized via a reaction of 4-fluorophenyl methyl ketone with hydroxylamine hydrochloride, followed by reduction. The process involves the use of sodium borohydride as a reducing agent to achieve a high yield. The reaction is carried out under mild conditions, and the product is purified by recrystallization from ethanol.

[3-(4-Fluorophenyl)-5-methyl-1,2-oxazol-4-yl]methanol finds applications in the pharmaceutical industry, particularly in the synthesis of certain medicinal compounds. It is also used in the chemical industry for the development of new materials, such as polymers and sensors, due to its unique structural features.

When handling [3-(4-Fluorophenyl)-5-methyl-1,2-oxazol-4-yl]methanol, it is essential to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Keep the compound away from sources of heat and direct sunlight. Store it in a well-ventilated area, preferably in a fume hood. In case of a spill, use appropriate containment and clean up materials to avoid environmental contamination. Always refer to the Material Safety Data Sheet (MSDS) for detailed safety information.