(+)-N,N'-(1R,2R)-1,2-DIAMINO-CYCLOHEXANEDIYLBIS(2-PYRIDINECARBOXAMIDE)(CAS: 218290-24-5)

N,N'-(1R,2R)-1,2-Cyclohexanediyldi(2-pyridinecarboxamide) is a crystalline solid with a molecular weight of approximately 332.19 g/mol. Its solubility in water is low, around 0.1 g/L. This compound exhibits good reactivity towards nucleophiles and can form stable complexes due to its amide and pyridine groups.

N,N'-(1R,2R)-1,2-Cyclohexanediyldi(2-pyridinecarboxamide) can be synthesized via a multistep process starting from 1,2-cyclohexanediamine and 2-pyridinecarboxylic acid. The key steps involve amide formation and selective functional group introduction, achieved with mild conditions and suitable catalysts. Yield and selectivity can be optimized with careful control of reaction parameters.

N,N'-(1R,2R)-1,2-Cyclohexanediyldi(2-pyridinecarboxamide) finds application in pharmaceuticals for its ability to form stable complexes with metal ions, which can enhance drug stability and bioavailability. It is also used in polymers for its excellent mechanical properties and in sensors for its sensitivity to certain chemical environments.

When handling N,N'-(1R,2R)-1,2-Cyclohexanediyldi(2-pyridinecarboxamide), it is crucial to wear appropriate personal protective equipment (PPE) such as gloves, safety goggles, and a lab coat. Work should be conducted in a well-ventilated area or a fume hood to minimize exposure. Spills should be cleaned up immediately using appropriate non-flammable solvents, and the area should be thoroughly rinsed. Always consult the Safety Data Sheet (SDS) for detailed handling and safety information.