1H-INDAZOLE-6-BORONIC ACID PINACOL ESTER(CAS: 861905-87-5)

6-(5,5-dimethyl-1,3,2-dioxaborinan-2-yl)-1H-indazole is a crystalline compound with a molecular weight of approximately 310.34 g/mol. It has low water solubility and moderate solubility in organic solvents. Chemically, it exhibits good stability under normal conditions but can react with strong acids or bases. It is typically used in organic synthesis and pharmaceutical applications.

6-(5,5-dimethyl-1,3,2-dioxaborinan-2-yl)-1H-indazole can be synthesized through a multistep process involving the use of boronic acids and indazoles. Common synthetic methods include Suzuki coupling reactions, utilizing palladium catalysts to achieve high yields and good selectivity. Detailed procedures and safety measures should be followed to ensure optimal results.

6-(5,5-dimethyl-1,3,2-dioxaborinan-2-yl)-1H-indazole is primarily used in pharmaceuticals for drug synthesis, polymer science for functional materials, and as a precursor in sensor and semiconductor manufacturing. Its unique structure makes it valuable in various chemical and industrial applications.

When handling 6-(5,5-dimethyl-1,3,2-dioxaborinan-2-yl)-1H-indazole, use appropriate personal protective equipment (PPE) including gloves, goggles, and a lab coat. Work in a fume hood to minimize inhalation risks. Store the compound in a cool, dry place away from strong acids, bases, and oxidizers. Always refer to the Safety Data Sheet (SDS) for detailed safety information and emergency procedures.