[(2R,5R)-5-Methyl-2-piperazinyl]methanol hydrochloride (1:1)(CAS: 1403898-63-4)

[(2R,5R)-5-Methyl-2-piperazinyl]methanol hydrochloride is a crystalline compound with a molecular weight of approximately 217.77 g/mol. It has a pKa of about 5.2 and is soluble in water and ethanol. It is moderately reactive, particularly towards bases and acids. The compound is stable under normal storage conditions but should be protected from moisture and light.

[(2R,5R)-5-Methyl-2-piperazinyl]methanol hydrochloride can be synthesized by reacting 5-methyl-2-piperazinol with hydrochloric acid. The reaction is typically carried out in an aqueous medium, and the product is isolated by crystallization. This method provides good yield and good selectivity for the desired enantiomer.

[(2R,5R)-5-Methyl-2-piperazinyl]methanol hydrochloride is used in the pharmaceutical industry for the synthesis of certain drugs. It is also utilized in the polymer industry for the modification of polymer properties and in the sensor industry for the development of new sensing materials. Additionally, it has applications in the semiconductor industry for the production of organic semiconductors.

When handling [(2R,5R)-5-Methyl-2-piperazinyl]methanol hydrochloride, it is important to wear appropriate personal protective equipment (PPE) such as gloves and goggles. Work should be carried out in a fume hood to minimize exposure. Spills should be cleaned up immediately using absorbent materials, and the area should be thoroughly ventilated. Always refer to the Safety Data Sheet (SDS) for detailed handling and emergency procedures.