N,N'-Dimethyl-5-pyrrolidinone-3-carboxamide(CAS: 89851-99-0)

N,N'-Dimethyl-5-pyrrolidinone-3-carboxamide is a colorless or light yellow liquid. It has a molecular weight of approximately 212.25 g/mol and a high solubility in organic solvents but is insoluble in water. It is moderately reactive, particularly towards bases and acids. The compound exhibits good thermal stability up to 120°C and is characterized by low viscosity and high boiling point (235°C).

N,N'-Dimethyl-5-pyrrolidinone-3-carboxamide can be synthesized by reacting 5-pyrrolidinone with dimethylamine in the presence of a suitable catalyst, such as a strong acid like hydrochloric acid. The reaction is typically conducted at room temperature, and the product can be isolated by filtration and recrystallization. The yield is around 85%-90%.

N,N'-Dimethyl-5-pyrrolidinone-3-carboxamide is primarily used in pharmaceuticals and polymers. It acts as a solvent and plasticizer in the pharmaceutical industry, and as a solvent and reaction medium in the polymer industry. It is also used in the development of sensors and semiconductors due to its unique chemical properties.

When handling N,N'-Dimethyl-5-pyrrolidinone-3-carboxamide, it is essential to wear appropriate personal protective equipment (PPE), including gloves, safety glasses, and a lab coat. The compound should be used in a well-ventilated area or under a fume hood to avoid inhalation. Spills should be cleaned up with absorbent materials, and the area should be flushed with water. It is recommended to consult the Safety Data Sheet (SDS) for detailed handling and disposal instructions.