4-Bromo-2-fluoro-6-(trifluoromethyl)aniline(CAS: 875664-46-3)

4-Bromo-2-fluoro-6-(trifluoromethyl)aniline is a crystalline solid with a molecular weight of approximately 335.03 g/mol. It has low water solubility and is highly reactive due to the presence of bromine, fluorine, and trifluoromethyl groups. The compound exhibits good thermal stability and can be used in various organic reactions.

4-Bromo-2-fluoro-6-(trifluoromethyl)aniline is often synthesized via electrophilic aromatic substitution reactions using appropriate bromine and fluorine sources, trifluoromethylating agents, and appropriate catalysts. The yield and selectivity of the reaction can be optimized through careful control of reaction conditions and reactant molar ratios.

4-Bromo-2-fluoro-6-(trifluoromethyl)aniline is used in the pharmaceutical industry for the synthesis of drug precursors and intermediates. It also finds applications in the polymer industry for the development of advanced materials, and in the semiconductor industry for the production of certain organic semiconductors.

When handling 4-Bromo-2-fluoro-6-(trifluoromethyl)aniline, it is essential to use personal protective equipment (PPE) including gloves, goggles, and a lab coat. Work should be conducted in a fume hood to minimize exposure. Spills should be cleaned up using appropriate absorbents and the material safety data sheet (MSDS) should be consulted for detailed spill procedures. Handling this compound requires careful attention due to its chemical reactivity and potential health hazards.