4-Iodo-5-methyl-1,2-oxazole(CAS: 7064-38-2)

4-Iodo-5-methyl-1,2-oxazole (CAS: 7064-38-2) is a white crystalline solid. It has a molecular weight of approximately 212.03 g/mol. This compound is slightly soluble in water but is more soluble in organic solvents like ethanol and acetone. It is relatively stable under normal conditions but can react with reducing agents. The compound is used in various synthetic transformations due to its reactivity with halogenated species.

4-Iodo-5-methyl-1,2-oxazole can be synthesized via the iodination of 5-methyl-1,2-oxazole with periodic acid in the presence of a suitable catalyst. The reaction is carried out under mild conditions, and the product is isolated via filtration and recrystallization. The yield is typically around 85%, and the purity can be enhanced through recrystallization.

4-Iodo-5-methyl-1,2-oxazole (CAS: 7064-38-2) is primarily used in pharmaceuticals for the synthesis of certain intermediates. It is also utilized in the development of sensors and in the production of some polymers. Additionally, it plays a role in the synthesis of materials for semiconductors, though its application in this area is less common.

When handling 4-Iodo-5-methyl-1,2-oxazole (CAS: 7064-38-2), it is important to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and lab coats. The compound should be handled in a well-ventilated area or a fume hood to minimize inhalation risks. In case of a spill, it should be carefully cleaned up using appropriate absorbent materials. Always consult the Safety Data Sheet (SDS) for detailed information on safe handling and emergency procedures.