4-(3-Formyl-2,5-dimethyl-1H-pyrrol-1-yl)benzoic acid(CAS: 52034-38-5)

4-(3-Formyl-2,5-dimethyl-1H-pyrrol-1-yl)benzoic acid is a crystalline solid with a molecular weight of approximately 284.32 g/mol. It has a high solubility in organic solvents like methanol and ethyl acetate, and low solubility in water. The compound is moderately reactive, showing good electrophilic character due to the presence of the formyl and carboxylic acid groups. It can form hydrogen bonds and other intermolecular interactions, contributing to its crystalline nature.

4-(3-Formyl-2,5-dimethyl-1H-pyrrol-1-yl)benzoic acid is synthesized by a multi-step process involving the condensation of 2,5-dimethylpyrrole with a benzaldehyde derivative followed by acylation and formylation. The reaction typically uses a catalytic amount of a suitable acid or base, with overall high yield and good selectivity. Common solvents include acetone and dichloromethane.

4-(3-Formyl-2,5-dimethyl-1H-pyrrol-1-yl)benzoic acid is used in the pharmaceutical industry for the synthesis of certain drugs and intermediates. It also finds applications in the polymer industry for enhancing the properties of certain polymer formulations. Additionally, it is utilized in the development of sensors and semiconductors, where its unique chemical properties contribute to its effectiveness.

When handling 4-(3-Formyl-2,5-dimethyl-1H-pyrrol-1-yl)benzoic acid, it is important to use personal protective equipment (PPE) including gloves, goggles, and a lab coat. Ensure proper ventilation and avoid inhalation or skin contact. Store the compound in a fume hood and maintain a well-ventilated area. In case of a spill, neutralize the acid with a base and dispose of according to local regulations. Always refer to the Safety Data Sheet (SDS) for detailed safety information.