4-(1-Piperazinyl)furo[3,2-c]pyridine(CAS: 81078-84-4)

4-(1-Piperazinyl)furo[3,2-c]pyridine is a crystalline solid with a molecular weight of approximately 240.29 g/mol. It has a solubility in water of 0.25 g/L at 25°C. This compound is known to be moderately reactive, particularly with acids and bases. It is stable under normal storage conditions, but care must be taken to avoid strong oxidizers and reducing agents.

4-(1-Piperazinyl)furo[3,2-c]pyridine is synthesized through a multistep process involving the condensation of furan and piperazine followed by a cyclization reaction. The synthesis typically requires the use of a catalyst such as triethylamine. The yield is around 75-80%, and the reaction is selective towards the desired product.

4-(1-Piperazinyl)furo[3,2-c]pyridine is primarily used in the pharmaceutical industry for the development of anti-inflammatory and anticonvulsant drugs. It is also utilized in the sensor industry due to its ability to detect specific analytes in various media. Additionally, it has potential applications in semiconductor technology as a dopant material.

When handling 4-(1-Piperazinyl)furo[3,2-c]pyridine, it is essential to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Work should be conducted in a well-ventilated area or a fume hood. Spills should be immediately cleaned up using appropriate absorbent materials. Always refer to the safety data sheet (SDS) for detailed handling and emergency procedures.