(2S)-2-Amino-2-(3-hydroxyadamantan-1-yl)acetic acid(CAS: 709031-29-8)

(2S)-2-Amino-2-(3-hydroxyadamantan-1-yl)acetic acid is a white crystalline solid with a molecular weight of approximately 342.45 g/mol. It has a melting point of 210-212°C and is soluble in water. This compound is known for its reactivity, particularly in acid-catalyzed reactions and can be used in peptide synthesis due to its amine functionality.

(2S)-2-Amino-2-(3-hydroxyadamantan-1-yl)acetic acid can be synthesized through protective group chemistry, where the hydroxyl group is protected to allow the formation of the amide bond. Common methods include using di-tert-butyldicarbonate (Boc2O) followed by aminolysis. This process yields a high degree of selectivity and purity, making it suitable for complex organic synthesis.

(2S)-2-Amino-2-(3-hydroxyadamantan-1-yl)acetic acid finds applications in the pharmaceutical industry for the synthesis of peptides and in the polymer industry for modifying polymer properties. It is also used in the development of sensors and as a building block in semiconductors.

When handling (2S)-2-Amino-2-(3-hydroxyadamantan-1-yl)acetic acid, wear appropriate personal protective equipment (PPE) including gloves, safety goggles, and a lab coat. Store in a fume hood to minimize inhalation risk. In case of spills, neutralize with an appropriate acid or base and clean up using absorbent materials. Refer to the Safety Data Sheet (SDS) for further safety information and emergency procedures.