7-Bromoimidazo[1,2-a]pyridine(CAS: 808744-34-5)

7-Bromoimidazo[1,2-a]pyridine is a solid with a crystalline form. Its molecular weight is approximately 212.02 g/mol. It has a limited water solubility and is soluble in organic solvents like DMSO and ethanol. The compound is moderately reactive, showing some basic properties due to the imidazole ring. It does not typically react with common reagents but may undergo thermal decomposition under certain conditions.

7-Bromoimidazo[1,2-a]pyridine can be synthesized via bromination of imidazo[1,2-a]pyridine using N-bromosuccinimide (NBS) in the presence of a suitable solvent like dimethylformamide (DMF). The reaction is typically performed at room temperature, and the product is purified by recrystallization from ethanol. The yield is around 70%, and the reaction is selective and efficient.

7-Bromoimidazo[1,2-a]pyridine is primarily used in the pharmaceutical industry for developing novel drug candidates. It is also explored in the polymer industry for its potential as a material component. Additionally, it shows promise in sensor technology for detecting specific compounds and in semiconductor applications for its electronic properties.

When handling 7-Bromoimidazo[1,2-a]pyridine, it is recommended to wear appropriate personal protective equipment (PPE) including gloves, eye protection, and a lab coat. Ensure the work is done in a well-ventilated fume hood to avoid inhalation. Spills should be cleaned up with care, using absorbent materials and disposing of them according to local regulations. Always refer to the Safety Data Sheet (SDS) for more detailed safety information and emergency procedures.