4-Bromo-N-methyl-2-pyrimidinamine(CAS: 1209458-16-1)

4-Bromo-N-methyl-2-pyrimidinamine (CAS: 1209458-16-1) is a crystalline solid with a molecular weight of approximately 226.03 g/mol. It has a high solubility in polar solvents such as methanol and acetonitrile. The compound reacts readily with nucleophiles due to the presence of the bromo and amine groups. It is stable under normal conditions but can be sensitive to moisture and air exposure.

4-Bromo-N-methyl-2-pyrimidinamine is typically synthesized via the reaction of 2-methyl-4-bromopyrimidine with methylamine in the presence of a base like sodium hydroxide. The process yields the desired product with good selectivity and moderate to high yield, depending on the reaction conditions.

4-Bromo-N-methyl-2-pyrimidinamine (CAS: 1209458-16-1) is used in the pharmaceutical industry for the synthesis of certain drug candidates. It is also utilized in the sensor technology sector for developing gas sensors and in semiconductor manufacturing for specific applications requiring precise chemical functionalities.

When handling 4-Bromo-N-methyl-2-pyrimidinamine (CAS: 1209458-16-1), it is essential to wear appropriate personal protective equipment (PPE) such as safety goggles, gloves, and a laboratory coat. The compound should be handled in a well-ventilated area or a fume hood to minimize exposure to air and moisture. Spills should be cleaned up using appropriate absorbents, and the area should be thoroughly washed down. Always refer to the Safety Data Sheet (SDS) for detailed handling and disposal information.