Methyl 3-(hydroxymethyl)cyclobutanecarboxylate(CAS: 89941-55-9)

Methyl 3-(hydroxymethyl)cyclobutanecarboxylate (CAS: 89941-55-9) is a crystalline compound with a molecular weight of approximately 134.14 g/mol. It has a low solubility in water but is soluble in organic solvents like ethanol and acetone. Chemically, it is reactive, particularly in esterification and hydrolysis reactions, making it useful in various chemical syntheses and pharmaceutical applications.

Methyl 3-(hydroxymethyl)cyclobutanecarboxylate (CAS: 89941-55-9) is typically synthesized through the addition of methanol to 3-chlorocyclobutanone in the presence of a base such as potassium hydroxide. The reaction is conducted in a polar aprotic solvent like dimethylformamide (DMF) at room temperature, yielding a mixture of diastereomers with high selectivity. The product is then isolated and purified by recrystallization.

Methyl 3-(hydroxymethyl)cyclobutanecarboxylate (CAS: 89941-55-9) is used in the pharmaceutical industry for the synthesis of certain drug molecules due to its reactivity. It is also found in the polymer industry as a monomer for the production of functional polymers. Additionally, it has applications in the production of sensors and as a reagent in semiconductor manufacturing processes.

When handling Methyl 3-(hydroxymethyl)cyclobutanecarboxylate (CAS: 89941-55-9), it is important to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. The compound should be stored in a cool, dry place away from direct sunlight and heat sources. In case of spillage, use a fume hood and proper disposal methods as outlined in the safety data sheet (SDS).