Methyl 5-bromo-1-benzofuran-2-carboxylate(CAS: 26028-36-4)

Methyl 5-bromo-1-benzofuran-2-carboxylate (CAS: 26028-36-4) is a crystalline compound with a molecular weight of approximately 268.04 g/mol. It has low water solubility and is moderately soluble in organic solvents. This compound is known for its reactivity, particularly towards nucleophiles, and is used in synthesis due to its bromine substituent, which can be used for further functionalization.

Methyl 5-bromo-1-benzofuran-2-carboxylate (CAS: 26028-36-4) is typically synthesized through the bromination of methyl 1-benzofuran-2-carboxylate using N-bromosuccinimide (NBS) in the presence of a radical initiator like azobisisobutyronitrile (AIBN). This method provides high selectivity and yield under suitable conditions.

Methyl 5-bromo-1-benzofuran-2-carboxylate (CAS: 26028-36-4) is used in the pharmaceutical industry for the synthesis of certain therapeutic compounds, as well as in the polymer industry for the development of advanced polymers with specific properties. It also finds applications in the production of sensors and semiconductors due to its functional groups.

When handling Methyl 5-bromo-1-benzofuran-2-carboxylate (CAS: 26028-36-4), it is essential to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and lab coat. Always work in a well-ventilated area or a fume hood to minimize exposure. Spills should be handled according to standard safety protocols, and the Material Safety Data Sheet (MSDS) should be consulted for detailed instructions.