Methyl 4-bromo-2,6-difluorobenzoate(CAS: 773134-11-5)

Methyl 4-bromo-2,6-difluorobenzoate is a crystalline solid with a molecular weight of approximately 300.04 g/mol. It has a low solubility in water but is more soluble in organic solvents like ethanol and dichloromethane. This compound is relatively stable under normal conditions but can react with reducing agents. It is used in organic synthesis, particularly in the preparation of other brominated and fluorinated compounds.

Methyl 4-bromo-2,6-difluorobenzoate can be synthesized by reacting 2,6-difluorobenzoic acid with methyl bromide in the presence of an appropriate base like sodium hydride. The reaction is carried out under anhydrous conditions to achieve high yield and selectivity. This method is commonly used in academic and industrial settings for the preparation of functionalized benzoic acid derivatives.

Methyl 4-bromo-2,6-difluorobenzoate is used in the pharmaceutical industry for the synthesis of intermediates in drug development. It is also utilized in the production of fluorinated polymers, which are important in the electronics and semiconductors industry. Additionally, it finds applications in the development of sensors and other chemical reagents.

When handling Methyl 4-bromo-2,6-difluorobenzoate, it is essential to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Work should be conducted in a fume hood to minimize exposure to fumes. Spills should be cleaned up immediately using appropriate absorbent materials. Always refer to the Safety Data Sheet (SDS) for detailed information on handling and emergency procedures.