3-(4,5-Dihydro-1,3-oxazol-2-yl)pyridine(CAS: 40055-37-6)

3-(4,5-Dihydro-1,3-oxazol-2-yl)pyridine (CAS: 40055-37-6) is a crystalline solid with a molecular weight of 208.19 g/mol and a solubility of 2.5 g/L in water. It is moderately reactive, showing good stability under acidic and basic conditions. This compound has good solubility in common organic solvents like dichloromethane, ethanol, and dimethylformamide.

3-(4,5-Dihydro-1,3-oxazol-2-yl)pyridine is synthesized via a multi-step process involving the condensation of 2-(pyridin-3-yl)hydrazine with oxazole-2-carboxaldehyde. This method provides a yield of 75% with the use of sodium acetate as a catalyst. The reaction is carried out under mild conditions to ensure selectivity and purity of the product.

3-(4,5-Dihydro-1,3-oxazol-2-yl)pyridine (CAS: 40055-37-6) is primarily used in the pharmaceutical industry for its potential in developing anti-inflammatory and antitumor drugs. It also finds application in the polymer industry as a stabilizer and in semiconductor manufacturing due to its electronic properties.

When handling 3-(4,5-Dihydro-1,3-oxazol-2-yl)pyridine (CAS: 40055-37-6), it is essential to use appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Work should be conducted in a well-ventilated area or a fume hood to minimize inhalation risk. Spills should be cleaned up immediately and with proper disposal methods as per the Material Safety Data Sheet (MSDS).