3-Neopentylisoxazol-5-amine(CAS: 749902-10-1)

3-Neopentylisoxazol-5-amine (CAS: 749902-10-1) is a white crystalline solid with a molecular weight of approximately 166.23 g/mol. It is slightly soluble in water and has good solubility in organic solvents such as methanol and ethanol. Chemically, it is stable under normal conditions but can react with strong acids to form ammonium salts. It is a versatile amine derivative with potential applications in pharmaceuticals and fine chemicals.

3-Neopentylisoxazol-5-amine (CAS: 749902-10-1) can be synthesized through the reaction of isoxazole-5-carbonyl chloride with 2,2-dimethylpropan-1-amine. The synthesis involves the use of a phase transfer catalyst and debenzylation steps. The yield is typically between 65% and 75%, with good selectivity for the desired product.

3-Neopentylisoxazol-5-amine (CAS: 749902-10-1) is primarily used in the pharmaceutical and fine chemical industries. It serves as a key intermediate in the synthesis of various drugs and can also be utilized in the development of new materials for sensors and semiconductors.

When handling 3-Neopentylisoxazol-5-amine (CAS: 749902-10-1), appropriate personal protective equipment (PPE) such as gloves, goggles, and lab coats should be worn. The compound should be stored in a cool, dry place away from direct sunlight. Spills should be cleaned up using appropriate absorbent materials and disposed of according to local regulations. Always refer to the Safety Data Sheet (SDS) for specific handling instructions and emergency procedures.