ent-Lurasidone Hydrochloride(CAS: 1448443-35-3)

Ent-Lurasidone Hydrochloride is a white to off-white crystalline powder. Its molecular weight is approximately 428.8 g/mol. It is soluble in water and slightly soluble in ethanol. Chemically, it is relatively stable but can undergo hydrolysis under acidic conditions. It has low reactivity with common laboratory reagents.

Ent-Lurasidone Hydrochloride is synthesized through a multi-step process involving the protection of a hydroxyl group, subsequent electrophilic aromatic substitution, and deprotection. The reaction typically requires catalysts such as palladium and bases like potassium phosphate. The overall yield is around 50-60%, with high selectivity towards the desired product.

Ent-Lurasidone Hydrochloride is primarily used in the pharmaceutical industry, specifically in the development and production of psychiatric medications. It is not commonly used in other industries such as polymers, sensors, or semiconductors.

When handling ent-Lurasidone Hydrochloride, it is recommended to wear appropriate personal protective equipment (PPE), including gloves and safety goggles. The substance should be stored in a cool, dry place away from direct sunlight. In case of a spill, it should be carefully cleaned up using appropriate methods, as per the Material Safety Data Sheet (MSDS). Always refer to the SDS for specific safety guidelines.